- Yang I, Corwin EJ, Brennan PA, Jordan S, Murphy JR, Dunlop A. The Infant Microbiome: Implications for Infant Health and Neurocognitive Development. Nursing research. 2016;65(1):76-88. doi:10.1097/NNR.0000000000000133.
- Mueller NT, Bakacs E, Combellick J, Grigoryan Z, Dominguez-Bello MG. The infant microbiome development: mom matters. Trends in molecular medicine. 2015;21(2):109-117. doi:10.1016/j.molmed.2014.12.002.
- Derrick M Chu et al. Maturation of the infant microbiome community structure and function across multiple body sites andin relation to mode of delivery, Nature Medicine (2017). DOI: 10.1038/nm.4272
- K. Aagaard et al. The Placenta Harbors a Unique Microbiome, Science Translational Medicine (2014).
- Pia S. Pannaraj, MD, MPH; Fan Li, PhD; Chiara Cerini, MD; et al. JAMA Pediatr. 2017;171(7):647-654. doi:10.1001/jamapediatrics.2017.0378
Thursday, July 20, 2017
However, a recently published study by researchers at Baylor College of Medicine found no differences in the microbiome of infants at 4 to 6 weeks of age between those delivered by C-section or born vaginally. According to the researchers, one explanation is that the microbiome may actually have been established in utero from the placenta during pregnancy and even undergone some maturation prior to birth. 3,4
Infants who are breastfed after birth continue to exhibit colonization and maturation of their gut microbiome. According to a recent study from UCLA5, breast milk contributed more than 25% of the bacteria to the infant gut with an additional 10% coming from the areolar skin - findings that were most pronounced during the first month of life. More importantly, infants who continued to breast feed through 6 months of age after the introduction of solid foods had a lower incidence of obesity and asthma. Although these findings need to be corroborated, they potentially add to the body of evidence supporting the benefits of breast feeding.
Judith Wolf, MD
Associate Director, WHEP
Tuesday, July 11, 2017
So why is this important? Because interestingly enough, of the 23.5 million Americans, 75% of those diagnosed with autoimmune diseases are women over the age of 50. The reasoning behind this has in the past been attributed to hormonal, genetic and epigenetic susceptibility, or chromosomal differences. These diseases ultimately impact various organ systems such as kidneys, GI tract, skin, etc.
Give a shout out to someone you know who is combating these autoimmune diseases and how they are living a complete life for our readers!